Recently, Professor Yang Jinghua’s team from the First Affiliated Hospital of Zhengzhou University collaborated with Professor Zhu Ping’s team from the Air Force Military Medical University and Professor Chen Liang’s team from Shanghai University and published the research paper“Cysteine carboxyethylation generates neoantigens to induce HLA-restricted autoimmunity”in Science,the international top journal. This paper announced a ubiquitin modification omics technique and discovered novel protein modifications and induction of restrictive autoimmunity. Professor Yang Jinghua is the co-corresponding author and the First Affiliated Hospital of Zhengzhou University is the first corresponding unit.